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Medication From Wikipedia, the free encyclopedia
Prasterone sulfate (brand names Astenile, Mylis, Teloin, others), also known as dehydroepiandrosterone sulfate (DHEA-S), is a naturally occurring androstane steroid which is marketed and used in Japan and other countries as a labor inducer in the treatment of insufficient cervical ripening and dilation during childbirth.[3][1][4][5][6][7][8][9] It is the C3β sulfate ester of prasterone (dehydroepiandrosterone; DHEA), and is known to act as a prohormone of DHEA and by extension of androgens and estrogens,[10] although it also has its own activity as a neurosteroid.[11] Prasterone sulfate is used medically as the sodium salt via injection and is referred to by the name sodium prasterone sulfate (JAN ).[9][12]
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Trade names | Astenile, Dastonil, Di Luo An, Dinistenile, Levospa, Mylis, Sinsurrene, Teloin |
Other names | DHEA sulfate; DHEA-S; Sodium prasterone sulfate; Sodium prasterone sulfate hydrate; KYH-3102; NSC-72822; PB-005[1][2] |
Routes of administration | Injection[3] |
Drug class | Androgen; Anabolic steroid; Androgen ester; Estrogen; Neurosteroid |
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Formula | C19H28O5S |
Molar mass | 368.49 g·mol−1 |
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Prasterone sulfate is available in Japan, Italy, Portugal, Argentina, and China.[9][13] Brand names include Astenile, Dastonil, Di Luo An, Dinistenile, Levospa, Mylis, Sinsurrene, and Teloin.[9][13]
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