Picrotoxin
Chemical compound / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about Picrotoxin?
Summarize this article for a 10 year old
Picrotoxin, also known as cocculin, is a poisonous crystalline plant compound. It was first isolated by the French pharmacist and chemist Pierre François Guillaume Boullay (1777–1869) in 1812.[1] The name "picrotoxin" is a combination of the Greek words "picros" (bitter) and "toxicon" (poison).[2] A mixture of two different compounds, picrotoxin occurs naturally in the fruit of the Anamirta cocculus plant, although it can also be synthesized chemically.
Clinical data | |||
---|---|---|---|
ATC code |
| ||
Identifiers | |||
CAS Number |
| ||
PubChem CID | |||
IUPHAR/BPS | |||
DrugBank |
| ||
ChemSpider |
| ||
UNII | |||
KEGG |
| ||
ChEBI | |||
ChEMBL | |||
CompTox Dashboard (EPA) | |||
ECHA InfoCard | 100.004.288 | ||
Chemical and physical data | |||
3D model (JSmol) | |||
| |||
| |||
NY (what is this?) (verify) |
Due to its interactions with the inhibitory neurotransmitter GABA, picrotoxin acts as a stimulant and convulsant. It mainly impacts the central nervous system, causing seizures and respiratory paralysis in high enough doses.