![cover image](https://wikiwandv2-19431.kxcdn.com/_next/image?url=https://upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Phosphocholine-zwitterion-3D-balls.png/640px-Phosphocholine-zwitterion-3D-balls.png&w=640&q=50)
Phosphocholine
Chemical compound / From Wikipedia, the free encyclopedia
Phosphocholine is an intermediate in the synthesis of phosphatidylcholine in tissues. Phosphocholine is made in a reaction, catalyzed by choline kinase, that converts ATP and choline into phosphocholine and ADP. Phosphocholine is a molecule found, for example, in lecithin.
![]() | |
![]() | |
Names | |
---|---|
Other names
Choline phosphate | |
Identifiers | |
| |
3D model (JSmol) |
|
ChemSpider |
|
MeSH | Phosphocholine |
PubChem CID |
|
UNII | |
CompTox Dashboard (EPA) |
|
| |
| |
Properties | |
C5H15NO4P | |
Molar mass | 184.151 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
In nematodes and human placentas, phosphocholine is selectively attached to other proteins as a posttranslational modification to suppress an immune response by their hosts.[1][2]
It is also one of the binding targets of C-reactive protein (CRP).[3] Thus, when a cell is damaged, CRP binds to phosphocholine, beginning the recognition and phagocytotic immunologic response.
Phosphocholine is a natural constituent of hens' eggs (and many other eggs) often used in biomimetic membrane studies.[4][5]