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Pho4
Protein-coding gene in the species Saccharomyces cerevisiae S288c / From Wikipedia, the free encyclopedia
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Pho4 is a protein with a basic helix-loop-helix (bHLH) transcription factor. It is found in S. cerevisiae and other yeasts.[2] It functions as a transcription factor to regulate phosphate responsive genes located in yeast cells.[3] The Pho4 protein homodimer is able to do this by binding to DNA sequences containing the bHLH binding site 5'-CACGTG-3'.[4] This sequence is found in the promoters of genes up-regulated in response to phosphate availability such as the PHO5 gene.[5]