Packed red blood cells
Red blood cells separated for blood transfusion / From Wikipedia, the free encyclopedia
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Packed red blood cells, also known as packed cells, are red blood cells that have been separated for blood transfusion.[1] The packed cells are typically used in anemia that is either causing symptoms or when the hemoglobin is less than usually 70–80 g/L (7–8 g/dL).[1][2][3] In adults, one unit brings up hemoglobin levels by about 10 g/L (1 g/dL).[4][5] Repeated transfusions may be required in people receiving cancer chemotherapy or who have hemoglobin disorders.[1] Cross-matching is typically required before the blood is given.[1] It is given by injection into a vein.[6]
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Other names | Stored packed red blood cells, packed cells, red cell concentrate, red cell component |
Routes of administration | IV |
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ChemSpider |
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Side effects include allergic reactions such as anaphylaxis, red blood cell breakdown, infection, volume overload, and lung injury.[1] With current preparation methods, the risk of viral infections such as hepatitis C and HIV/AIDS are less than one in a million.[1] Packed red blood cells are produced from whole blood or by apheresis.[7] They typically last for three to six weeks.[7]
The widespread use of packed red blood cells began in the 1960s.[8] It is on the World Health Organization's List of Essential Medicines.[9][10] A number of other versions also exist including whole blood, leukocyte reduced red blood cells, and washed red blood cells.[1]