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PRKCE
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
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This article is about the enzyme. For the OAuth security extension PKCE, see OAuth § Security_issues.
Protein kinase C epsilon type (PKCε) is an enzyme that in humans is encoded by the PRKCE gene.[5][6] PKCε is an isoform of the large PKC family of protein kinases that play many roles in different tissues. In cardiac muscle cells, PKCε regulates muscle contraction through its actions at sarcomeric proteins, and PKCε modulates cardiac cell metabolism through its actions at mitochondria. PKCε is clinically significant in that it is a central player in cardioprotection against ischemic injury and in the development of cardiac hypertrophy.
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