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Chemical compound From Wikipedia, the free encyclopedia
Norgesterone, also known as norvinodrel or vinylestrenolone and sold under the brand name Vestalin, is a progestin medication which was formerly used in birth control pills for women but is now no longer marketed.[1][2][3][4] It was used in combination with the estrogen ethinylestradiol.[2][3][4] It is taken by mouth.[5][6]
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Trade names | Vestalin (with EE ) |
Other names | Norvinodrel; Vinylestrenolone; Vinilestrenolone; Vinylnoretynodrel; 17α-Vinylestr-5(10)-en-17-ol-3-one; 17α-Vinyl-δ5(10)-19-nortestosterone |
Routes of administration | By mouth |
Drug class | Progestogen; Progestin |
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Formula | C20H28O2 |
Molar mass | 300.442 g·mol−1 |
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Norgesterone is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone.[7] It has no androgenic activity.[7]
Norgesterone was first described in 1962.[8][9] It is no longer available.[10]
Norgesterone was used in combination with ethinylestradiol in birth control pills to prevent pregnancy.[2] It is no longer available.[10]
Norgesterone is a progestogen, and hence is an agonist of the progesterone receptor.[7] Unlike related progestins, it is virtually devoid of androgenic activity in animal assays.[7]
Norgesterone, also known as 17α-vinyl-δ5(10)-19-nortestosterone or as 17α-vinylestr-5(10)-en-17β-ol-3-one, is a synthetic estrane steroid and a derivative of testosterone and 19-nortestosterone.[1] Analogues of norgesterone include norvinisterone (17α-vinyl-19-nortestosterone) and vinyltestosterone (17α-vinyltestosterone).[1]
Norgesterone is the generic name of the drug and its INN .[1] It has also been referred to as norvinodrel, vinylestrenolone, and vinylnoretynodrel.[1][11]
Norgesterone was marketed in combination with ethinylestradiol, an estrogen, as a birth control pill under the brand name Vestalin.[2][3][4]
Norgesterone is no longer marketed and hence is no longer available in any country.[10]
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