N,N-Diisopropylethylamine
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N,N-Diisopropylethylamine, or Hünig's base, is an organic compound that is a tertiary amine. It is named after the German chemist Siegfried Hünig [de]. It is used in organic chemistry as a non-nucleophilic base. It is commonly abbreviated as DIPEA, DIEA, or i-Pr2NEt.
Quick Facts Names, Identifiers ...
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Names | |||
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Preferred IUPAC name
N-Ethyl-N-(propan-2-yl)propan-2-amine | |||
Other names
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Identifiers | |||
3D model (JSmol) |
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ChemSpider |
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ECHA InfoCard | 100.027.629 | ||
EC Number |
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MeSH | N,N-diisopropylethylamine | ||
PubChem CID |
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UNII | |||
UN number | 2733 | ||
CompTox Dashboard (EPA) |
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Properties | |||
C8H19N | |||
Molar mass | 129.247 g·mol−1 | ||
Appearance | Colorless liquid | ||
Odor | Fishy, ammoniacal | ||
Density | 0.742 g mL−1 | ||
Melting point | −50 to −46 °C (−58 to −51 °F; 223 to 227 K) | ||
Boiling point | 126.6 °C; 259.8 °F; 399.7 K | ||
4.01 g/L (at 20 °C) | |||
Vapor pressure | 4.1 kPa (at 37.70 °C) | ||
Refractive index (nD) |
1.414 | ||
Hazards | |||
GHS labelling: | |||
Danger | |||
H225, H301, H314, H412 | |||
P210, P273, P280, P301+P310, P305+P351+P338, P310 | |||
Flash point | 10 °C (50 °F; 283 K) | ||
Explosive limits | 0.7–6.3% | ||
Lethal dose or concentration (LD, LC): | |||
LD50 (median dose) |
200–500 mg kg−1 (oral, rat) | ||
Related compounds | |||
Related amines |
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Related compounds |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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