Myeloproliferative neoplasm
Overproduction of blood cells in the bone marrow / From Wikipedia, the free encyclopedia
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Myeloproliferative neoplasms (MPNs) are a group of rare blood cancers in which excess red blood cells, white blood cells or platelets are produced in the bone marrow. Myelo refers to the bone marrow, proliferative describes the rapid growth of blood cells and neoplasm describes that growth as abnormal and uncontrolled.
Quick Facts Other names, Specialty ...
Myeloproliferative neoplasm | |
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Other names | Myeloproliferative diseases (MPDs) |
Myelogram of someone with a myeloproliferative disorder. | |
Specialty | Hematology and oncology |
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The overproduction of blood cells is often associated with a somatic mutation, for example in the JAK2, CALR, TET2, and MPL gene markers.
In rare cases, some MPNs such as primary myelofibrosis may accelerate and turn into acute myeloid leukemia.[1]