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Minaxolone
Chemical compound / From Wikipedia, the free encyclopedia
Minaxolone (CCI-12923) is a neuroactive steroid which was developed as a general anesthetic but was withdrawn before registration due to toxicity seen with long-term administration in rats, and hence was never marketed.[1][2][3] It is a positive allosteric modulator of the GABAA receptor,[4] as well as, less potently, a positive allosteric modulator of the glycine receptor.[4][5]
Quick Facts Clinical data, Other names ...
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Other names | 11α-(Dimethylamino)-2β-ethoxy-3α-hydroxy-5α-pregnan-20-one |
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Formula | C25H43NO3 |
Molar mass | 405.623 g·mol−1 |
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