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Minaprine
Chemical compound / From Wikipedia, the free encyclopedia
Minaprine (INN, USAN, BAN; brand names Brantur, Cantor) is a monoamine oxidase inhibitor antidepressant drug that was used in France for the treatment of depression until it was withdrawn from the market in 1996 because it caused convulsions.[2][3]
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Quick Facts Clinical data, AHFS/Drugs.com ...
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AHFS/Drugs.com | International Drug Names |
Routes of administration | Oral |
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Elimination half-life | 2-2.5 hours |
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ECHA InfoCard | 100.043.012 ![]() |
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Formula | C17H22N4O |
Molar mass | 298.390 g·mol−1 |
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A study found that it acts as a reversible inhibitor of MAO-A (RIMA) in rats.[4] It has also been found to weakly inhibit acetylcholinesterase in rat brain (striatum) homogenates.[5]
It has demonstrated significant antibiotic activity against M. chelonae and M. abscessus in tests with antibiotic resistant bacteria.[6]