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Met-enkephalin
Chemical compound / From Wikipedia, the free encyclopedia
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Met-enkephalin, also known as metenkefalin (INN), sometimes referred to as opioid growth factor (OGF),[1] is a naturally occurring, endogenous opioid peptide that has opioid effects of a relatively short duration. It is one of the two forms of enkephalin, the other being leu-enkephalin. The enkephalins are considered to be the primary endogenous ligands of the δ-opioid receptor, due to their high potency and selectivity for the site over the other endogenous opioids.[2]
Quick Facts Names, Identifiers ...
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Names | |
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IUPAC name
(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoic acid | |
Other names
[Met]enkephalin; [Met5]enkephalin; L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionine | |
Identifiers | |
3D model (JSmol) |
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ECHA InfoCard | 100.055.741 ![]() |
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MeSH | Enkephalin,+Methionine |
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CompTox Dashboard (EPA) |
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Properties | |
C27H35N5O7S | |
Molar mass | 573.67 g·mol−1 |
log P | 0.607 |
Acidity (pKa) | 3.234 |
Basicity (pKb) | 10.763 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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