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Malathion
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Malathion is an organophosphate insecticide which acts as an acetylcholinesterase inhibitor. In the USSR, it was known as carbophos, in New Zealand and Australia as maldison and in South Africa as mercaptothion.
Quick Facts Names, Identifiers ...
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Names | |
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IUPAC name
Diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioate | |
Other names
2-(Dimethoxyphosphinothioylthio) butanedioic acid diethyl ester Malathion Carbofos Maldison Mercaptothion Ortho malathion | |
Identifiers | |
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3D model (JSmol) |
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ChEBI | |
ChEMBL | |
ChemSpider |
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DrugBank |
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ECHA InfoCard | 100.004.089 ![]() |
KEGG |
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PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C10H19O6PS2 | |
Molar mass | 330.358021 |
Appearance | Clear colorless liquid |
Density | 1.23 g/cm3 |
Melting point | 2.9 °C (37.2 °F; 276.0 K) |
Boiling point | 156 to 157 °C (313 to 315 °F; 429 to 430 K) at 0.7 mmHg |
145 mg/L at 20 °C[1] | |
Solubility | Soluble in ethanol and acetone; very soluble in ethyl ether |
log P | 2.36 (octanol/water)[2] |
Pharmacology | |
P03AX03 (WHO) QP53AF12 (WHO) | |
Hazards | |
Flash point | 163 °C; 325 °F; 436 K (greater than)[3] |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
290 mg/kg (rat, oral) 190 mg/kg (mouse, oral) 570 mg/kg (guinea pig, oral)[4] |
LC50 (median concentration) |
84.6 mg/m3 (rat, 4 hr)[4] |
LCLo (lowest published) |
10 mg/m3 (cat, 4 hr)[4] |
NIOSH (US health exposure limits): | |
PEL (Permissible) |
TWA 15 mg/m3 [skin][3] |
REL (Recommended) |
TWA 10 mg/m3 [skin][3] |
IDLH (Immediate danger) |
250 mg/m3[3] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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