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Macrocytosis
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For the kelp genus, see Macrocystis.
Macrocytosis is a condition where red blood cells are larger than normal.[1] These enlarged cells, also known as macrocytes, are defined by a mean corpuscular volume (MCV) that exceeds the upper reference range established by the laboratory and hematology analyzer (usually >110 fL).[2] Upon examination of a peripheral blood smear under microscope, these macrocytes appear larger than standard erythrocytes. It’s noteworthy that macrocytosis is a common morphological feature in neonatal peripheral blood.[3] The presence of macrocytosis can indicate a range of conditions, from benign, treatable illnesses to more serious underlying disorders.
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Quick Facts Other names, Specialty ...
Macrocytosis
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Other names | Macrocytes |
Specialty | Hematology |
Symptoms | Shortness of breath, weakness, heart murmur, tachycardia |
Causes | Vitamin B12 deficiency, Folic acid deficiency, Malabsorption, Alcoholism |
Risk factors | Bone marrow failure, hematologic malignancy |
Diagnostic method | Symptoms, Complete blood count, Peripheral blood smear, Vitamin B12 level, Red cell folate level |
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