MT-ND4
Mitochondrial gene coding for a protein involved in the respiratory chain / From Wikipedia, the free encyclopedia
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MT-ND4 is a gene of the mitochondrial genome coding for the NADH-ubiquinone oxidoreductase chain 4 (ND4) protein.[5] The ND4 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain.[6] Variations in the MT-ND4 gene are associated with age-related macular degeneration (AMD), Leber's hereditary optic neuropathy (LHON), mesial temporal lobe epilepsy (MTLE) and cystic fibrosis.[7][8][9][10]
Quick Facts ND4, Identifiers ...
ND4 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | ND4, MTMT-NADH dehydrogenase, subunit 4 (complex I), NADH dehydrogenase subunit 4 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 516003; MGI: 102498; HomoloGene: 38240; GeneCards: ND4; OMA:ND4 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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