MT-ND3
Mitochondrial protein-coding gene whose product is involved in the respiratory chain / From Wikipedia, the free encyclopedia
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MT-ND3 is a gene of the mitochondrial genome coding for the NADH dehydrogenase 3 (ND3) protein.[5] The ND3 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain.[6] Variants of MT-ND3 are associated with Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), Leigh's syndrome (LS) and Leber's hereditary optic neuropathy (LHON).[7][8]
Quick Facts ND3, Identifiers ...
ND3 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | ND3, MTMT-NADH dehydrogenase, subunit 3 (complex I), NADH dehydrogenase subunit 3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 516002; MGI: 102499; HomoloGene: 5018; GeneCards: ND3; OMA:ND3 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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