MT-ND1
Mitochondrial gene coding for a protein involved in the respiratory chain / From Wikipedia, the free encyclopedia
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MT-ND1 is a gene of the mitochondrial genome coding for the NADH-ubiquinone oxidoreductase chain 1 (ND1) protein.[5] The ND1 protein is a subunit of NADH dehydrogenase, which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain.[6] Variants of the human MT-ND1 gene are associated with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), Leigh's syndrome (LS), Leber's hereditary optic neuropathy (LHON) and increases in adult BMI.[7][8][9]
Quick Facts ND1, Identifiers ...
ND1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | ND1, MTMT-NADH dehydrogenase, subunit 1 (complex I), NADH dehydrogenase subunit 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 516000; MGI: 101787; HomoloGene: 5011; GeneCards: ND1; OMA:ND1 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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