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MALAT1
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MALAT 1 (metastasis associated lung adenocarcinoma transcript 1) also known as NEAT2 (noncoding nuclear-enriched abundant transcript 2) is a large, infrequently spliced non-coding RNA, which is highly conserved amongst mammals and highly expressed in the nucleus.[3] It regulates the expression of metastasis-associated genes.[4] It also positively regulates cell motility via the transcriptional and/or post-transcriptional regulation of motility-related genes.[5] MALAT1 may play a role in temperature-dependent sex determination in the Red-eared slider turtle (Trachemys scripta).[6]
Quick Facts Identifiers, Aliases ...
MALAT1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | MALAT1, HCN, LINC00047, MALAT-1, NCRNA00047, NEAT2, PRO2853, mascRNA, metastasis associated lung adenocarcinoma transcript 1 (non-protein coding), metastasis associated lung adenocarcinoma transcript 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 607924; GeneCards: MALAT1; OMA:MALAT1 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Quick Facts Conserved secondary structure in Metastasis associated lung adenocarcinoma transcript 1, Identifiers ...
Conserved secondary structure in Metastasis associated lung adenocarcinoma transcript 1 | |
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![]() Predicted secondary structure and sequence conservation of MALAT1 | |
Identifiers | |
Symbol | MALAT1 |
Rfam | RF01871 |
Other data | |
RNA type | Gene; |
Domain(s) | Eukaryota; |
GO | GO:2000147 |
SO | SO:0001263 |
PDB structures | PDBe |
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