Lokivetmab, trade name Cytopoint, is a monoclonal antibody used to treat atopic dermatitis in dogs.[1] It acts against interleukin 31 (IL-31),[2] which is a cytokine involved in causing itchiness (pruritus).[2] Lokivetmab is administered by subcutaneous injection; each dose is effective for four to eight weeks.[3]
| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Target | interleukin 31 (IL-31) |
| Clinical data | |
| Trade names | Cytopoint |
| Routes of administration | subcutaneous injection |
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| Legal status | |
| Legal status |
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| Identifiers | |
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The United States Department of Agriculture (USDA) approved lokivetmab (manufactured by Zoetis and sold under the trade name Cytopoint) in December 2016,[3] and it was approved by the European Medicines Agency in 2017.[4] Lokivetmab was the first monoclonal antibody to be approved for use in animals in the European Union.[4]
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