Lithium orotate
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Lithium orotate (C5H3LiN2O4) is a salt of orotic acid and lithium. It is available as the monohydrate, LiC5H3N2O4·H2O.[1] In this compound, lithium is non-covalently bound to an orotate ion, rather than to a carbonate or other ion, and like other salts, dissociates in solution to produce free lithium ions. It is marketed as a dietary supplement, though it has been researched minimally between 1973–1986 to treat certain medical conditions, such as alcoholism[2] and Alzheimer's disease.
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AHFS/Drugs.com | Monograph |
Routes of administration | Oral |
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ECHA InfoCard | 100.023.711 |
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Formula | C5H3LiN2O4 |
Molar mass | 162.03 g·mol−1 |
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While lithium orotate is capable of providing lithium to the body,[3] like lithium carbonate and other lithium salts, there are no systematic reviews supporting the efficacy of lithium orotate and it is not approved by the U.S. Food and Drug Administration (FDA) for the treatment of any medical condition.