The following is a list of prominent people who were born in Worcester, Massachusetts, lived in Worcester, or for whom Worcester is a significant part of their identity.
- Richard T. Antoun (1932–2009), Professor Emeritus of Anthropology at Binghamton University
- Harvey Ball (1921–2001), inventor of the smiley face
- Alan T. Busby (1895–1992), educator and first African-American alumnus of the University of Connecticut
- Harold W. Chase (1922–1982), educator and United States military officer
- Robert Goddard (1882–1945), father of modern rocketry
- G. Stanley Hall (1846–1924), first president of Clark University
- John Kneller (1916–2009), English-American professor and fifth President of Brooklyn College
- David Green (born 1963), president of Colby College
- Leonard Morse (born 1929), university professor of clinical medicine
- Lawrence Park (1873–1924), art historian, architect, and genealogist
- Francis E. Reed (1852–1917), inventor and industrialist who founded F.E. Reed & Co.
- Daniel B. Wesson (1825–1906), gunsmith, co-founder of Smith & Wesson
- John Wolcott Adams (1874–1925), artist
- Edith Ella Baldwin (1846–1920), artist
- H. Jon Benjamin, actor best known as the voices of Sterling Archer on Archer, Bob Belcher on Bob's Burgers, and Can of Vegetables in the Wet Hot American Summer franchise
- Christopher Boffoli, photographer
- Elbridge Boyden, architect of Mechanics Hall
- Zara Cully, actress best known for The Jeffersons
- Stephen DiRado, photographer
- Stephen C. Earle, architect
- Paul Fontaine, abstractist colorist painter
- Joslyn Fox, drag queen, contestant on Rupaul’s Drag Race season 6
- Ryan Idol, adult film actor
- Rita Johnson, actress, co-starred opposite Spencer Tracy in Edison, The Man
- Jean Louisa Kelly, actress from Yes, Dear
- Arthur Kennedy, Oscar-nominated, Tony Award-winning actor
- Dorothy Stratton King, painter and printmaker
- Diane and Elaine Klimaszewski, actresses and models best known as the "Coors Light Twins"
- Jarrett J. Krosoczka, children's book author and illustrator; his Punk Farm optioned by DreamWorks Animation
- Denis Leary, actor and comedian
- Tom Lewis, artist and activist
- Joyner Lucas, American rapper
- John Lurie, actor, musician, and composer
- Nora Marlowe (1915–1977), actress
- Eddie Mekka, actor best known for playing Carmine Ragusa on Laverne and Shirley
- Alisan Porter, former child actress and winner of Season 10 of The Voice
- Terri Priest, artist
- Sam Qualiana, actor and filmmaker involved with many low-budget horror films, including Snow Shark (2012)
- Joyce Reopel, artist
- Renee Sands, former child actress and singer from Kids Incorporated and Wild Orchid
- Sam Seder, podcast host of The Majority Report, actor, writer and director
- Joseph Skinger, silversmith, sculptor
- Doug Stanhope, comedian known for abrasive style and for The Man Show
- Lewis Stone (1879–1953), actor, The Secret Six, Grand Hotel, Andy Hardy series
- Erik Per Sullivan, actor, Malcolm in the Middle
- Wu Tsang, filmmaker, artist, and performer
- David Whitney, art curator
- Alicia Witt, actress, singer-songwriter
- Hildegard Woodward, children's book illustrator
- Jerry Azumah, former NFL defensive back[1]
- Tyler Beede (born 1993), baseball pitcher for the San Francisco Giants
- Frank Carroll, US figure skater and coach, 1960 graduate of the College of the Holy Cross, actor[2]
- Tim Collins, relief pitcher for the Kansas City Royals[3]
- Alana Cook, soccer player for the United States national team[4]
- Bob Cousy, Hall of Fame basketball player; attended the College of the Holy Cross; currently lives in Worcester[5]
- Jay Cutler, former professional bodybuilder and 4x Mr. Olympia
- Ken Doane, professional wrestler[6]
- Oliver Drake, relief pitcher who's a free agent
- Rich Gedman, Boston Red Sox catcher, manager of the Worcester Tornadoes[7]
- Bill Guerin, former Pittsburgh Penguins right winger[8]
- Aaron Haddad, professional wrestler in WWE[9]
- Tom Heinsohn, NBA Hall of Fame, Boston Celtics great; attended College of Holy Cross
- Gordon Lockbaum, attended Holy Cross College; twice finished in the top five in the Heisman Trophy balloting[10]
- Dwayne McClain, former NBA/Professional basketball player. Starred at Villanova in the early/mid 1980s. Attended Holy Name Catholic Central
- Tom Poti, former NHL defenseman[11]
- J.P. Ricciardi, MLB executive, former general manager of the Toronto Blue Jays[12]
- José Antonio Rivera, WBA light middleweight champion[citation needed]
- Richard Rodgers II, 3rd-string Tight End for the Philadelphia Eagles; played for St. John's High School
- Edwin Rodríguez, boxer[13]
- Rosy Ryan – was a professional baseball pitcher. He played ten seasons. Best remembered for his time with the World Series Champion New York Giants
- Tanyon Sturtze, former MLB pitcher[14]
- Major Taylor, track cycling champion[15]
- Bill Toomey, gold medal decathlete, 1968 Olympics; attended Worcester Academy
- Leah Van Dale, professional wrestler better known by her ring name Carmella
- Vinnie Yablonski, NFL player[16]
- Stephen Nedoroscik, an artistic gymnast and a two-time Olympic medalist
- John Adams, popular composer
- Duncan Arsenault, musician
- Norman Bailey, big band trumpet player from The Lawrence Welk Show
- Jaki Byard, jazz pianist, composer and recording artist[17]
- Frank Capp, jazz drummer and bandleader
- Luke Caswell, better known as Cazwell, an LGBT rapper
- Wendell Culley, jazz trumpeter from Worcester who played with Noble Sissle, Lionel Hampton, and Count Basie's Orchestra, and many others[18]
- Don Fagerquist, jazz trumpeter
- Four Year Strong, rock band
- J. Geils, lead in J. Geils Band, attended Worcester Polytechnic Institute
- J. Geils Band, formed in Worcester as a fraternity party band at Worcester Polytechnic Institute, as Snoopy and the Sopwith Camels
- Georgia Gibbs, 1950s pop singer
- Duke Levine, guitarist[19]
- The Hotelier, rock band
- Jordan Knight, member of the boy band New Kids On The Block
- Joyner Lucas, rapper
- Arun Luthra, jazz saxophonist, konnakol artist, composer, arranger, band leader[20]
- Miriam "Mamie" Moffitt, jazz pianist and band leader of Mamie Moffitt and Her Five Jazz Hounds, the first professional jazz ensemble in Worcester[21]
- Orpheus, band that enjoyed popularity in the 1960s and early 1970s
- Cole Porter, Broadway composer, student at Worcester Academy ca. 1912, born in Peru, Indiana
- Andy Ross, guitarist for rock band OK Go
- Maureen Steele, pop singer and songwriter, one of the very few white artists signed to Motown during the mid 1980s
- Einar Swan, multi-instrumental jazz musician and songwriter of "When Your Lover Has Gone"[22]
- Boots Ward, jazz drummer, band leader, and Worcester jazz club owner[23]
- Charles Allen (1797–1869), United States Congressman from Massachusetts[24]
- George Bancroft, 17th United States Secretary of the Navy, founder of the US Naval Academy at Annapolis, author of the first comprehensive history of the United States[25]
- John Binienda, Massachusetts state legislator[26]
- Alexander H. Bullock, Governor of Massachusetts (1866–1868)[27]
- Kate Campanale, member of Massachusetts House of Representatives from District 17[28]
- John Curtis Chamberlain, US Representative[29]
- Dorothea Dix, reformer and activist
- Dwight Foster, Massachusetts Attorney General and Associate Justice of the Massachusetts Supreme Judicial Court[30]
- Roger Sherman Baldwin Foster, lawyer[31]
- Emma Goldman, Lithuanian-American anarchist; owned ice cream parlor in Worcester[32]
- Thomas Wentworth Higginson, abolitionist, literary mentor to Emily Dickinson[33]
- Abbie Hoffman, radical activist[34]
- Abby Kelley Foster, abolitionist, suffragette[35]
- Joseph T. Higgins, member of the New York State Assembly
- Jim McGovern, US Representative from Massachusetts's 2nd congressional district
- Levi Lincoln Sr., American revolutionary
- Levi Lincoln Jr., Governor of Massachusetts
- William D. Mullins, state representative and baseball player[36]
- Albert L. Nash, politician and businessman[37]
- Richard Neal, US Representative from Massachusetts's 1st congressional district
- Kenneth P. O'Donnell, Appointments Secretary and Political Adviser to President John F. Kennedy[38]
- Robert Owens, businessman and Massachusetts state senator
- John Rucho, politician and businessman[39]
- Charles F. Sullivan, Mayor of Worcester and Lieutenant Governor of Massachusetts, 1949–1953
- Benjamin Swan, longest-serving Vermont State Treasurer[40]
- Charles G. Washburn, member of the U.S. House of Representatives
- Jane G. Austin, writer
- Mike Barnicle, print and broadcast journalist, social and political commentator
- S. N. Behrman, playwright, author of memoir The Worcester Account
- Robert Benchley, writer and member of the Algonquin Round Table
- Elizabeth Bishop, poet and writer
- John D. Casey, novelist and translator
- John Dufresne, novelist and screenwriter
- Alice Morse Earle, writer
- Esther Forbes, writer
- Samuel Fuller, screenwriter, producer and director
- John Michael Hayes, writer of the Alfred Hitchcock films Rear Window, To Catch a Thief, The Trouble with Harry, and The Man Who Knew Too Much
- Isabel Hornibrook, children's literature writer
- Omar Jimenez, CNN reporter, known for being arrested on live TV while reporting on the George Floyd protests in Minneapolis
- Aidan “Turtleboy” Kearney, author and investigative journalist
- Stanley Kunitz, Poet Laureate
- Frank O'Hara, poet
- Charles Olson, modernist poet
- Charlie Pierce (born 1953), American writer/journalist, and panelist on NPR's Wait Wait... Don't Tell Me
- Normand Poirier, writer
- Olive Higgins Prouty, writer, known for "Now, Voyager" and "Stella Dallas"
- Ernest Lawrence Thayer, poet and journalist, known for "Casey at the Bat"
- Isaiah Thomas, publisher of the Massachusetts Spy
- Stanley Woodward, newspaper editor and sportswriter
- Lillian Asplund, last survivor of the RMS Titanic who remembered the actual sinking
- William Austin Burt, 19th-century explorer and surveyor in Michigan
- Nathaniel Bar-Jonah, convicted child molester, possible serial killer and cannibal
- Timothy Bigelow, Revolutionary War patriot
- Jonas Clark, founder of Clark University
- Edmund L. Daley (1883–1968), U.S. Army major general[41]
- Edgar C. Erickson (1896–1989), United States Army Major General and Chief of the National Guard Bureau
- Catherine Fiske (1784-1837), school founder
- John Stanley Grauel (1917–1986), Christian Zionist leader
- Samuel Fisk Green (1822–1884), physician and medical missionary, served with the American Ceylon Mission 1847–1873
- Samuel R. Heywood, founder of the Heywood Boot & Shoe Company
- Myra Kraft, philanthropist, wife of New England Patriots owner Bob Kraft
- Royal B. Lord (1899–1963), United States military officer
- Joe Morrone, Connecticut Huskies soccer coach
- Charley Parkhurst, stagecoach driver and horseman
- Irving Price, co-founder of Fisher Price toys and games
- Michael Ritchie, artistic director
- George Edward Rueger (1929–2019), Roman Catholic bishop
- Stephen Salisbury III, founder of the Worcester Art Museum
- Richard B. Sellars (1915–2010), Chairman and CEO of Johnson & Johnson[42]
- Madeline Singas, American attorney and jurist.
- Ichabod Washburn, founder of Worcester Polytechnic Institute
- Steven N. Wickstrom, Army National Guard major general who commanded the 42nd Infantry Division[43]
- Stillman Witt (1808–1875), Ohio railroad and steel executive, banker[44]
- Geoffrey Zakarian, Iron Chef, Food Network Channel celebrity chef[45]
"Bob Cousy". Pro-Basketball Reference . Com. Retrieved May 15, 2014.
"Ken Doane". 2013, Canoe Inc. Archived from the original on January 15, 2013. Retrieved May 15, 2014.{{cite web}}
: CS1 maint: unfit URL (link)
"Rich Gedman". Pro-Baseball Reference.com. Retrieved May 15, 2014.
"Aaron Haddad". 2013, Canoe Inc. Archived from the original on November 1, 2013. Retrieved May 15, 2014.{{cite web}}
: CS1 maint: unfit URL (link)
"Tom Poti". Hockey Reference.com. Retrieved May 15, 2014.
"Marshall Taylor". 2000 - 2002 Major Taylor Association, Inc. Retrieved May 15, 2014.
Williamson Sneade, David "Chet" (January 5, 2013). ""When Your Lover Has Gone"". Worcester Songwriters of the Great American Songbook. Retrieved March 11, 2022.
Who Was Who in America, Historical Volume, 1607–1896. Marquis Who's Who. 1967.
Davis, William Thomas (1900), History of the Judiciary of Massachusetts: Including the Plymouth and Massachusetts Colonies, The Province of Massachusetts Bay, and The Commonwealth, Boston, MA: The Boston Book Company, p. 194
'1973-1974 Public Officials of the Commonwealth of Massachusetts, Biographical Sketch of Albert L. Nash, pg. 252
1977-1978 Public Officials of the Commonwealth of Massachusetts Biographical Sketch of John Rucho, pg. 282