Liquid biopsy
Sampling and analysis of non-solid biological tissues / From Wikipedia, the free encyclopedia
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A liquid biopsy, also known as fluid biopsy or fluid phase biopsy, is the sampling and analysis of non-solid biological tissue, primarily blood.[1][2] Like traditional biopsy, this type of technique is mainly used as a diagnostic and monitoring tool for diseases such as cancer, with the added benefit of being largely non-invasive. Liquid biopsies may also be used to validate the efficiency of a cancer treatment drug by taking multiple samples in the span of a few weeks. The technology may also prove beneficial for patients after treatment to monitor relapse.[3]
Liquid biopsy | |
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Synonyms | Fluid biopsy |
Purpose | analysis of non-solid biological tissue |
The clinical implementation of liquid biopsies is not yet widespread but is becoming standard of care in some areas.[4]
Liquid biopsy refers to the molecular analysis in biological fluids of nucleic acids, subcellular structures, especially exosomes, and, in the context of cancer, circulating tumor cells.[5]