![cover image](https://wikiwandv2-19431.kxcdn.com/_next/image?url=https://upload.wikimedia.org/wikipedia/commons/thumb/2/22/Lipoblast_features%252C_annotated.png/640px-Lipoblast_features%252C_annotated.png&w=640&q=50)
Lipoblast
From Wikipedia, the free encyclopedia
A lipoblast is a precursor cell for an adipocyte.[1]
![Thumb image](http://upload.wikimedia.org/wikipedia/commons/thumb/2/22/Lipoblast_features%2C_annotated.png/640px-Lipoblast_features%2C_annotated.png)
Alternate terms include adipoblast[2] and preadipocyte.[3]
Early stages are almost indistinguishable from fibroblasts.[4]
- Lipoblasts (white arrow) and lipocytes (black arrow), in a case of lipoblastoma
- Histopathology of liposarcoma, H&E stain, with the main features:[5]
- Spindle cells with enlarged, hyperchromatic nuclei.
- Apparently univacuolated adipocytes (may look normal).
- Lipoblasts (multivacuolated), but neither necessary nor sufficient for diagnosis of liposarcoma. - Lipid-laden histiocytes may mimic lipoblasts, but have lightly eosinophilic cytoplasm and a small normochromatic nuclei which are not hollowed out from the lipid vacuoles.[6]