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Langerhans cell
Cell type / From Wikipedia, the free encyclopedia
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Not to be confused with the cells of the islets of Langerhans in the pancreas, or Langhans giant cell.
A Langerhans cell (LC) is a tissue-resident macrophage of the skin[2] once thought to be a resident dendritic cell.[3] These cells contain organelles called Birbeck granules. They are present in all layers of the epidermis and are most prominent in the stratum spinosum.[4] They also occur in the papillary dermis, particularly around blood vessels,[4] as well as in the mucosa of the mouth, foreskin, and vaginal epithelium.[5] They can be found in other tissues, such as lymph nodes, particularly in association with the condition Langerhans cell histiocytosis (LCH).
Quick Facts Details, System ...
Langerhans cell | |
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![]() Section of skin showing large numbers of Langerhans cells in the epidermis. (M. ulcerans infection, S100 immunoperoxidase stain.) | |
Details | |
System | Immune system |
Location | Skin and mucosa |
Function | Dendritic cell |
Identifiers | |
MeSH | D007801 |
FMA | 63072 |
Anatomical terms of microanatomy |
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