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Iclaprim
Chemical compound / From Wikipedia, the free encyclopedia
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Iclaprim is an antibiotic drug candidate that is active against Gram positive organisms.[1][2] It is administered intravenously.[3]: 3
Quick Facts Clinical data, Routes ofadministration ...
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Routes of administration | intravenous |
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ECHA InfoCard | 100.130.860 ![]() |
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Formula | C19H22N4O3 |
Molar mass | 354.410 g·mol−1 |
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Chirality | Racemic mixture |
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In vitro, iclaprim is active against methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Staphylococcus aureus (VRSA), strains of Streptococcus pneumoniae resistant to several common antibiotics, and some Gram-negative bacteria.[4] It is of the diaminopyrimidine dihydrofolate reductase (DHFR)-inhibiting type.