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Chemical compound From Wikipedia, the free encyclopedia
Hyzetimibe is a pharmaceutical drug that inhibits cholesterol absorption.[1][2] It targets the NPC1-like intracellular cholesterol transporter 1.[2]
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Other names | HS-25 |
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Formula | C25H21F2NO3 |
Molar mass | 421.444 g·mol−1 |
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it reduces plasma levels of low-density lipoprotein cholesterol (LDL-C) by blocking the Niemann-Pick C1-like 1 protein, a transporter mainly found in the intestine that allows dietary cholesterol to enter the body from the intestinal lumen.[3]
In China, it is used as a lipid-lowering agent and it has efficacy similar to ezetimibe.[4]
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