Hymecromone

Hymecromone
Clinical data
Other names	4-Methylumbelliferone
AHFS/Drugs.com	International Drug Names
ATC code	A05AX02 (WHO) ;
Identifiers
	IUPAC name 7-Hydroxy-4-methylchromen-2-one;
CAS Number	90-33-5 ;
PubChem CID	5280567;
DrugBank	DB07118 ;
ChemSpider	4444190 ;
UNII	3T5NG4Q468;
KEGG	D00170 ;
ChEBI	CHEBI:17224 ;
ChEMBL	ChEMBL12208 ;
CompTox Dashboard (EPA)	DTXSID8025670 ;
ECHA InfoCard	100.001.806
Chemical and physical data
Formula	C10H8O3
Molar mass	176.171 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=CC(=O)OC2=C1C=CC(=C2)O;
	InChI InChI=1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3 ; Key:HSHNITRMYYLLCV-UHFFFAOYSA-N ;
	(verify)

Hymecromone (4-methylumbelliferone) is a drug used in bile therapy. It is used as choleretic and antispasmodic drugs and as a standard for the fluorometric determination of enzyme activity.^[1]

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Hymecromone is a crystalline solid with a melting point of 194–195 °C. It is soluble in methanol and glacial acetic acid.

[1]
Yang Y, Hamaguchi K (April 1980). "Hydrolysis of 4-methylumbelliferyl N-acetyl-chitotrioside catalyzed by hen and turkey lysozymes. pH dependence of the kinetics constants". Journal of Biochemistry. 87 (4): 1003–14. doi:10.1093/oxfordjournals.jbchem.a132833. PMID 7390976.

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[pmid7390976-1] [1]
Yang Y, Hamaguchi K (April 1980). "Hydrolysis of 4-methylumbelliferyl N-acetyl-chitotrioside catalyzed by hen and turkey lysozymes. pH dependence of the kinetics constants". Journal of Biochemistry. 87 (4): 1003–14. doi:10.1093/oxfordjournals.jbchem.a132833. PMID 7390976.

[1]

Hymecromone

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