Hantzsch ester
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Hantzsch ester refers to an organic compound with the formula HN(MeC=C(CO2Et))2CH2 where Me = methyl (CH3) and Et = ethyl (C2H5). It is a light yellow solid. The compound is an example of a 1,4-dihydropyridine. It is named after Arthur Rudolf Hantzsch who described its synthesis in 1881. The compound is a hydride donor, e.g., for reduction of imines to amines. It is a synthetic analogue of NADH, a naturally occurring dihydropyridine.[1]
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Other names
Diludine, 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester | |
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ECHA InfoCard | 100.013.237 |
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CompTox Dashboard (EPA) |
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Properties | |
C13H19NO4 | |
Molar mass | 253.298 g·mol−1 |
Appearance | white or colorless solid |
Melting point | 182–183 °C (360–361 °F; 455–456 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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