Haemophilia C
Medical condition / From Wikipedia, the free encyclopedia
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Haemophilia C (also known as plasma thromboplastin antecedent (PTA) deficiency or Rosenthal syndrome) is a mild form of haemophilia affecting both sexes, due to factor XI deficiency.[4] It predominantly occurs in Ashkenazi Jews. It is the fourth most common coagulation disorder after von Willebrand's disease and haemophilia A and B. In the United States, it is thought to affect 1 in 100,000 of the adult population, making it 10% as common as haemophilia A.[1][5]
Quick Facts Hemophilia C, Other names ...
Hemophilia C | |
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Other names | Plasma thromboplastin antecedent (PTA) deficiency, Rosenthal syndrome |
Haemophilia C caused by deficiency in Factor XI[1] | |
Specialty | Haematology |
Symptoms | Oral bleeding[2] |
Causes | Deficiency of coagulation factor XI[1] |
Diagnostic method | Prothrombin time[1] |
Prevention | Physical activity precautions[1] |
Treatment | tranexamic acid[3] |
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