HLA-A43
Human leukocyte antigen serotype / From Wikipedia, the free encyclopedia
HLA-A43 (A43) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α43 subset of HLA-A α-chains. For A43, the alpha "A" chain are encoded by the HLA-A*43 allele group and the β-chain are encoded by B2M locus.[1] This group currently is dominated by A*4301. A43 and A*43 are almost synonymous in meaning. A43 is a split antigen of the broad antigen serotype A10. A43 is a sister serotype of A25, A26, A34, and A66.
Further information: History and naming of human leukocyte antigens
Quick Facts About, Protein ...
HLA-A43 | ||||||||||||||||
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(MHC Class I, A cell surface antigen) | ||||||||||||||||
About | ||||||||||||||||
Protein | transmembrane receptor/ligand | |||||||||||||||
Structure | αβ heterodimer | |||||||||||||||
Subunits | HLA-A*4301, β2-microglobulin | |||||||||||||||
Older names | A10 | |||||||||||||||
Subtypes | ||||||||||||||||
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Alleles link-out to IMGT/HLA database at EBI |
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A43 is more common in Africa and SouthWest Asia. A43 is believed to have been formed by a single gene conversion between another HLA-A and the A*2601 allele.[2].