Guanidine
Chemical compound / From Wikipedia, the free encyclopedia
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Guanidine is the compound with the formula HNC(NH2)2. It is a colourless solid that dissolves in polar solvents. It is a strong base that is used in the production of plastics and explosives. It is found in urine predominantly in patients experiencing renal failure.[4] A guanidine moiety also appears in larger organic molecules, including on the side chain of arginine.
Quick Facts Names, Identifiers ...
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Names | |||
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Preferred IUPAC name
Guanidine[1] | |||
Other names
Iminomethanediamine | |||
Identifiers | |||
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3D model (JSmol) |
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506044 | |||
ChEBI | |||
ChEMBL | |||
ChemSpider |
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DrugBank |
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ECHA InfoCard | 100.003.656 ![]() | ||
EC Number |
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100679 | |||
MeSH | Guanidine | ||
PubChem CID |
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UNII | |||
CompTox Dashboard (EPA) |
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Properties | |||
CH5N3 | |||
Molar mass | 59.072 g·mol−1 | ||
Melting point | 50 °C (122 °F; 323 K) | ||
log P | −1.251 | ||
Basicity (pKb) | 0.4[2] | ||
Conjugate acid | Guanidinium | ||
Thermochemistry | |||
Std enthalpy of formation (ΔfH⦵298) |
−57 – −55 kJ mol−1 | ||
Std enthalpy of combustion (ΔcH⦵298) |
−1.0511 – −1.0531 MJ mol−1 | ||
Pharmacology | |||
Pharmacokinetics: | |||
7–8 hours | |||
Hazards | |||
Lethal dose or concentration (LD, LC): | |||
LD50 (median dose) |
475 mg/kg (oral, rat)[3] | ||
Related compounds | |||
Related compounds |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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