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Ground glass hepatocyte
From Wikipedia, the free encyclopedia
In liver pathology, a ground glass hepatocyte, abbreviated GGH, is a liver parenchymal cell with a flat hazy and uniformly dull appearing cytoplasm on light microscopy. The cytoplasm's granular homogeneous eosinophilic staining is caused by the presence of HBsAg.
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The appearance is classically associated with abundant hepatitis B antigen in the endoplasmic reticulum, but may also be drug-induced.[1][2] In the context of hepatitis B, GGHs are only seen in chronic infections, i.e. they are not seen in acute hepatitis B.