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Gliclazide
Chemical compound / From Wikipedia, the free encyclopedia
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Gliclazide, sold under the brand name Diamicron among others, is a sulfonylurea type of anti-diabetic medication, used to treat type 2 diabetes.[7] It is used when dietary changes, exercise, and weight loss are not enough.[4] It is taken by mouth.[7]
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Trade names | Diamicron, Diaprel, Azukon, others[1] |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
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Routes of administration | By mouth |
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Elimination half-life | 10.4 hours |
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ECHA InfoCard | 100.040.221 ![]() |
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Formula | C15H21N3O3S |
Molar mass | 323.41 g·mol−1 |
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Melting point | 180 to 182 °C (356 to 360 °F) |
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Side effect may include low blood sugar, vomiting, abdominal pain, rash, and liver problems.[4][7] Use by those with significant kidney problems or liver problems or who are pregnant is not recommended.[7][4] Gliclazide is in the sulfonylurea family of medications.[7] It works mostly by increasing the release of insulin.[7]
Gliclazide was patented in 1966 and approved for medical use in 1972.[8] It is on the World Health Organization's List of Essential Medicines.[9] It is not available for sale in the United States.[10]