Fresolimumab
Monoclonal antibody / From Wikipedia, the free encyclopedia
Fresolimumab (GC1008) is a human monoclonal antibody[1] and an immunomodulator. It is intended for the treatment of idiopathic pulmonary fibrosis (IPF), focal segmental glomerulosclerosis, and cancer[2][3] (kidney cancer and melanoma).
Quick Facts Monoclonal antibody, Type ...
Monoclonal antibody | |
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Type | Whole antibody |
Source | Human |
Target | TGF beta 1, 2 and 3 |
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Formula | C6392H9926N1698O2026S44 |
Molar mass | 144388.22 g·mol−1 |
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It binds to and inhibits all isoforms of the protein transforming growth factor beta (TGF-β).[2]