French flag model
Biological model / From Wikipedia, the free encyclopedia
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The French flag model is a conceptual definition of a morphogen, described by Lewis Wolpert in the 1960s.[2][3] A morphogen is defined as a signaling molecule that acts directly on cells (not through serial induction) to produce specific cellular responses dependent on morphogen concentration. During early development, morphogen gradients generate different cell types in distinct spatial order. French flag patterning is often found in combination with others: vertebrate limb development is one of the many phenotypes exhibiting French flag patterning overlapped with a complementary pattern (in this case Turing pattern).[4]