Flucloxacillin
Penicillin / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about Flucloxacillin?
Summarize this article for a 10 year old
Flucloxacillin, also known as floxacillin, is an antibiotic used to treat skin infections, external ear infections, infections of leg ulcers, diabetic foot infections, and infection of bone.[4] It may be used together with other medications to treat pneumonia, and endocarditis.[4] It may also be used prior to surgery to prevent Staphylococcus infections.[4] It is not effective against methicillin-resistant Staphylococcus aureus (MRSA).[5] It is taken by mouth or given by injection into a vein or muscle.[4]
Clinical data | |
---|---|
Trade names | Floxapen, others[1] |
Other names | BRL-2039 |
AHFS/Drugs.com | International Drug Names |
Pregnancy category |
|
Routes of administration | By mouth, intramuscular, intravenous, intrapleural, intraarticular |
ATC code | |
Legal status | |
Legal status | |
Pharmacokinetic data | |
Bioavailability | 50–70% |
Metabolism | Liver |
Elimination half-life | 0.75–1 hour[3] |
Excretion | Kidney[3] |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
DrugBank | |
UNII | |
KEGG | |
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.023.683 |
Chemical and physical data | |
Formula | C19H17ClFN3O5S |
Molar mass | 453.87 g·mol−1 |
3D model (JSmol) | |
| |
| |
(verify) |
Common side effects include an upset stomach.[4] Other side effects may include muscle or joint pains, shortness of breath, and liver problems.[4][6] It appears to be safe during pregnancy and breastfeeding.[4] It should not be used in those who are allergic to penicillin.[4] It is a narrow-spectrum beta-lactam antibiotic of the penicillin class.[6] It is similar in effect to cloxacillin and dicloxacillin, being active against penicillinase forming bacteria.[7]
Flucloxacillin was patented in 1961.[8] It is not commonly used in the United States or Canada as of 2011.[9]