![cover image](https://wikiwandv2-19431.kxcdn.com/_next/image?url=https://upload.wikimedia.org/wikipedia/commons/thumb/e/ec/Fructose.svg/640px-Fructose.svg.png&w=640&q=50)
Essential fructosuria
Medical condition / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about Essential fructosuria?
Summarize this article for a 10 year old
SHOW ALL QUESTIONS
Essential fructosuria, caused by a deficiency of the enzyme hepatic fructokinase, is a clinically benign condition characterized by the incomplete metabolism of fructose in the liver, leading to its excretion in urine.[2] Fructokinase (sometimes called ketohexokinase) is the first enzyme involved in the degradation of fructose to fructose-1-phosphate in the liver.[3]
Quick Facts Other names, Specialty ...
Essential fructosuria | |
---|---|
Other names | Ketohexokinase deficiency[1] |
![]() | |
Fructose | |
Specialty | Medical genetics |
Close
This defective degradation does not cause any clinical symptoms, fructose is either excreted unchanged in the urine or metabolized to fructose-6-phosphate by alternate pathways in the body, most commonly by hexokinase in adipose tissue and muscle.[2]