Esophagogastric junction outflow obstruction
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Esophagogastric junction outflow obstruction (EGJOO) is an esophageal motility disorder characterized by increased pressure where the esophagus connects to the stomach at the lower esophageal sphincter. EGJOO is diagnosed by esophageal manometry. However, EGJOO has a variety of etiologies; evaluating the cause of obstruction with additional testing, such as upper endoscopy, computed tomography (CT imaging), or endoscopic ultrasound may be necessary.[2] When possible, treatment of EGJOO should be directed at the cause of obstruction. When no cause for obstruction is found (functional EGJOO), observation alone may be considered if symptoms are minimal. Functional EGJOO with significant or refractory symptoms may be treated with pneumatic dilation, per-oral endoscopic myotomy (POEM), or botulinum toxin injection.
Esophagogastric junction outflow obstruction | |
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Other names | EGJOO |
Specialty | Gastroenterology |
Symptoms | Asymptomatic, dysphagia, chest pain |
Usual onset | 56-57 years |
Types | Mechanical, functional, medication, artifact[1] |
Risk factors | Female gender, overweight |
Diagnostic method | High resolution manometry (esophageal manometry) |
Differential diagnosis | Achalasia |
Treatment | Pneumatic dilation, Per-oral endoscopic myotomy (POEM), botulinum toxin injection |
Prognosis | Depends on etiology |
Frequency | Unknown |