Ellipticine
Chemical compound / From Wikipedia, the free encyclopedia
Ellipticine is a tetracyclic alkaloid first extracted from trees of the species Ochrosia elliptica and Rauvolfia sandwicensis,[5][6] which inhibits the enzyme topoisomerase II via intercalative binding to DNA.[7]
Quick Facts Names, Identifiers ...
Names | |
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Preferred IUPAC name
5,11-Dimethyl-6H-pyrido[4,3-b]carbazole | |
Identifiers | |
3D model (JSmol) |
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ChEBI | |
ChemSpider | |
ECHA InfoCard | 100.007.514 |
EC Number |
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KEGG | |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C17H14N2 | |
Molar mass | 246.313 g·mol−1 |
Appearance | Yellow crystalline powder[1] |
Density | 1.257±0.06 g/cm3[2] |
Melting point | 316–318 °C (601–604 °F; 589–591 K)[2] |
Very low[3] | |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards |
toxic |
GHS labelling: | |
[4] | |
H301[4] | |
P264, P270, P301+P310, P321, P330, P405, P501[4] | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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