![cover image](https://wikiwandv2-19431.kxcdn.com/_next/image?url=https://upload.wikimedia.org/wikipedia/commons/thumb/2/21/Efrapeptin_F.svg/640px-Efrapeptin_F.svg.png&w=640&q=50)
Efrapeptin
From Wikipedia, the free encyclopedia
Efrapeptins are peptides produced by fungi in the genus Tolypocladium that have antifungal, insecticidal, and mitochondrial ATPase inhibitory activities.[1] They are produced via a biosynthetic pathway similar to, but simpler than, the ciclosporin pathway with nonribosomal peptide synthase (NRPS) and/or polyketide synthase (PKS) being the key elements.[2]
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The amino acid sequences of efrapeptins are:[citation needed]
- Efrapeptin F: Ac-Pip-Aib-Pip-Aib-Aib-Leu-bAla-Gly-Aib-Aib-Pip-Aib-Ala-Leu-Iva-Unk
- Efrapeptin G: Ac-Pip-Aib-Pip-Iva-Aib-Leu-bAla-Gly-Aib-Aib-Pip-Aib-Ala-Leu-Iva-Unk
- Aib: 2-methylalanine; Iva: 2-ethylalanine; Unk: does not match to a known amino acid