Dimitri Kullmann
British neurologist From Wikipedia, the free encyclopedia
British neurologist From Wikipedia, the free encyclopedia
Dimitri Michael Kullmann (born 1958)[1] FRS FMedSci MAE is a professor of neurology at the UCL Institute of Neurology,[2] University College London (UCL), and leads the synaptopathies initiative funded by the Wellcome Trust.[5] Kullmann is a member of the Queen Square Institute of Neurology Department of Clinical and Experimental Epilepsy[6] and a consultant neurologist at the National Hospital for Neurology and Neurosurgery.[3][7]
Dimitri Kullmann | |
|---|---|
Dimitri Kullmann at the Royal Society, London, 2018 | |
| Born | Dimitri Michael Kullmann 1958 (age 65–66)[1] London, England[1] |
| Education | Lycée Français Charles de Gaulle[1] |
| Alma mater | University of Oxford (BM BCh, DPhil) |
| Awards | Baly Medal (2017)[2] |
| Scientific career | |
| Fields | |
| Institutions | |
| Thesis | Central actions of muscle receptors (1984) |
| Doctoral advisor | Julian Jack[4] |
| Website | www |
Kullmann was educated at the Lycée Français Charles de Gaulle[1] and studied physiology at Balliol College, Oxford[1] where he was awarded a Bachelor of Arts (BA) degree and a Doctor of Philosophy degree.[4] He studied and trained at the University of Oxford and St Thomas's Hospital Medical School at the University of London.[2] His postgraduate research was supervised by Julian Jack.[4]
Kullmann's research[3][7] investigates how synapses function in health and disease.[8] His laboratory helped to show how neurotransmitters activate different receptor subtypes in and around synapses, and resolved some controversies about the mechanisms of long-term changes in synaptic strength.[8] Genetic and autoimmune disorders of synaptic proteins (‘synaptopathies’) provide insights into the mechanisms of a broad range of neurological diseases including epilepsy and migraine.[8] Together with his colleagues, Kullmann has used these insights to devise gene therapy strategies that could be used to treat intractable epilepsy.[8][3]
The Kullmann lab[3][7] has contributed to the discovery and elucidation of silent synapses,[9] glutamate spillover, tonic inhibition,[10] long-term potentiation in interneurons,[11] neurological channelopathies[12] and Synaptopathies, gene therapy for epilepsy,[13] and mechanisms of neural oscillations.[14] Kullmann served as the editor-in-chief of the scientific journal Brain between 2014 and 2020[15] and is on the editorial board of the journal Neuron.[16] Before working at UCL, he did postdoctoral research with Roger Nicoll at the University of California, San Francisco.[2]
Kullmann was awarded the University Gold Medal in Medicine by the University of London, in 1986.[2] and the Baly Medal by the Royal College of Physicians in 2017.[2] He was elected a Guarantor of Brain in 2000,[17] elected a Fellow of the Academy of Medical Sciences (FMedSci) in 2001,[18] a Corresponding Fellow of the American Neurological Association in 2013,[19] a member of the Academia Europaea (MAE) in 2017[20] and a Fellow of the Royal Society (FRS) in 2018.[8] He was awarded the 2023 Basic Science Research Award by the American Epilepsy Society.[21]
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