Difenoxin
Chemical compound / From Wikipedia, the free encyclopedia
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Difenoxin (Motofen, R-15403) is an opioid drug used, often in combination with atropine, to treat diarrhea.[2] It is the principal metabolite of diphenoxylate.[3][4]: 558
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Other names | Difenoxin, Motofen |
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Formula | C28H28N2O2 |
Molar mass | 424.544 g·mol−1 |
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It was first approved in the US in 1978[5] and in 1980 in the former West Germany.[6]: 485
Difenoxin crosses the blood brain barrier and induces some euphoria; it is often sold with or administered with atropine to reduce the potential for abuse and overdose.[2]