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Dexmedetomidine
Anxiolytic, sedative, and pain medication / From Wikipedia, the free encyclopedia
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Dexmedetomidine, sold under the trade name Precedex among others, is a drug used in humans for sedation.[3] Veterinarians use dexmedetomidine for similar purposes in treating cats, dogs, and horses.[7][8] It is also used in humans to treat acute agitation associated with schizophrenia or bipolar I or II disorder.[4]
Quick Facts Clinical data, Trade names ...
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Trade names | Precedex, Dexdor, Igalmi, others |
AHFS/Drugs.com | Monograph |
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Routes of administration | Intravenous, transmucosal, intranasal, sublingual |
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Protein binding | 94% (mostly albumin)[3] |
Metabolism | Near complete hepatic metabolism to inactive metabolites |
Elimination half-life | 2–4 hours[6] |
Excretion | Urine |
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ECHA InfoCard | 100.119.391 ![]() |
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Formula | C13H16N2 |
Molar mass | 200.285 g·mol−1 |
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Similar to clonidine, it is a sympatholytic drug that acts as an agonist of α2-adrenergic receptors in certain parts of the brain.[9] It was developed by Orion Pharma.