Loading AI tools
Chemical compound From Wikipedia, the free encyclopedia
Daigremontianin is a bufadienolide. Bufadienolides are steroids and cardiac glycoside aglycones (meaning that they bind with carbohydrates to form cardiac glycosides) that are similar to cardenolides, differing only in the structure of the C-17 substituent on the D ring. This chemical has been found to be toxic in experiments on mice.[1][2] It is one of five bufadienolides that have been isolated from Kalanchoe daigremontiana.
Names | |
---|---|
IUPAC name
(1β,3β,5β,11α)-1,3,5-(ethylidynetris(oxy)-11,14-dihydroxy-12,19-dioxobufa-20,22-dienolide | |
Identifiers | |
3D model (JSmol) |
|
ChemSpider | |
PubChem CID |
|
UNII | |
CompTox Dashboard (EPA) |
|
| |
| |
Properties | |
C26H30O9 | |
Molar mass | 486.517 g·mol−1 |
Density | 1.49 g/mL |
Boiling point | 695.2 °C (1,283.4 °F; 968.4 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
Crassulaceans are one of the prime sources of bufadienolide cardiac glycosides (including daigremontianin) responsible for an estimated 33% of cattle mortalities related to plant poisoning in South Africa. Crassulacean bufadienolides cause cardiac poisoning, but repeated small doses cause a condition called cotyledonosis,[3] an intoxication affecting nervous and muscular systems of small animals, particularly, sheep in the Karoo area of South Africa.
Seamless Wikipedia browsing. On steroids.
Every time you click a link to Wikipedia, Wiktionary or Wikiquote in your browser's search results, it will show the modern Wikiwand interface.
Wikiwand extension is a five stars, simple, with minimum permission required to keep your browsing private, safe and transparent.