Cross syndrome

Cross syndrome (also known as "Cross–McKusick–Breen syndrome", "hypopigmentation and microphthalmia", and "oculocerebral-hypopigmentation syndrome") is an extremely rare disorder characterized by white skin, blond hair with yellow-gray metallic sheen, small eyes with cloudy corneas, jerky nystagmus, gingival fibromatosis and severe intellectual disability and physical retardation.^{[2]: 867–8}

Cross syndrome
Other names	Oculocerebral hypopigmentation syndrome, Cross type[1]
Cross syndrome is inherited in an autosomal recessive manner
Specialty	Endocrinology

It was characterized in 1967.^[3]

See also

• Oculocerebrocutaneous syndrome
• List of cutaneous conditions

References

1. RESERVED, INSERM US14-- ALL RIGHTS. "Orphanet: Oculocerebral hypopigmentation syndrome, Cross type". www.orpha.net. Retrieved 19 April 2019.{{cite web}}: CS1 maint: numeric names: authors list (link)
2. James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
3. Cross HE, McKusick VA, Breen W (March 1967). "A new oculocerebral syndrome with hypopigmentation". J. Pediatr. 70 (3): 398–406. doi:10.1016/S0022-3476(67)80137-9. PMID 4959856.

External links

• "Cross' syndrome". Whonamedit?. Retrieved 2023-03-10.