Corey–Seebach reaction
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The Corey–Seebach reaction, or Seebach Umpolung is a name reaction of organic chemistry that allows for acylation by converting aldehydes into lithiated 1,3-dithianes. The lithiated 1,3-dithianes serves as an acyl anion equivalent, undergoing alkylation with electrophiles.[1] The reaction is named in honor of its discoverers, Elias J. Corey and Dieter Seebach.
Quick Facts Identifiers ...
Corey–Seebach reaction | |
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Named after | Elias James Corey Dieter Seebach |
Reaction type | Coupling reaction |
Identifiers | |
Organic Chemistry Portal | corey-seebach-reaction |
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