Claisen condensation
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Not to be confused with Claisen rearrangement or Claisen–Schmidt condensation.
The Claisen condensation is a carbon–carbon bond forming reaction that occurs between two esters or one ester and another carbonyl compound in the presence of a strong base. The reaction produces a β-keto ester or a β-diketone.[1] It is named after Rainer Ludwig Claisen, who first published his work on the reaction in 1887.[2][3][4] The reaction has often been displaced by diketene-based chemistry, which affords acetoacetic esters.[5]
Quick Facts Reaction, Conditions ...
Claisen condensation | |||||||||||||
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Named after | Rainer Ludwig Claisen | ||||||||||||
Reaction type | Condensation reaction | ||||||||||||
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Typical solvents | R'-OH | ||||||||||||
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Organic Chemistry Portal | claisen-condensation | ||||||||||||
RSC ontology ID | RXNO:0000043 | ||||||||||||
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