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From Wikipedia, the free encyclopedia
Cephalotaxus alkaloids are natural products characterized by pentacyclic structure.
These alkaloids are commonly found in the plum yew species (Cephalotaxus), especially in the Japanese plum-yew.[1]
The most important representative is cephalotaxin. Other notable representatives include harringtonine and homoharringtonine.[1]
Harringtonine and homoharringtonine exhibit antitumor activity and act against murine leukemia cells. They serve as protein and DNA biosynthesis inhibitors and are used against acute myelocytoxic leukemia.[1]
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