Liver carboxylesterase 1 also known as carboxylesterase 1 (CES1, hCE-1 or CES1A1) is an enzyme that in humans is encoded by the CES1 gene.[5][6] The protein is also historically known as serine esterase 1 (SES1), monocyte esterase and cholesterol ester hydrolase (CEH). Three transcript variants encoding three different isoforms have been found for this gene.[6] The various protein products from isoform a, b and c range in size from 568, 567 and 566 amino acids long, respectively.
Quick Facts CES1, Available structures ...
CES1 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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1MX1, 1MX5, 1MX9, 1YA4, 1YA8, 1YAH, 1YAJ, 2DQY, 2DQZ, 2DR0, 2H7C, 2HRQ, 2HRR, 3K9B, 4AB1, 5A7F, 5A7H, 5A7G |
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Identifiers |
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Aliases | CES1, ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, hCE-1, carboxylesterase 1 |
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External IDs | OMIM: 114835 MGI: 2148202 HomoloGene: 35606 GeneCards: CES1 |
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EC number | 3.1.1.1 |
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Wikidata |
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CES1 is present in most tissues with higher levels in the liver and low levels in the gastrointestinal tract.[7]