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Calcinosis cutis
Medical condition in which calcium deposits form in the skin / From Wikipedia, the free encyclopedia
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Calcinosis cutis is an uncommon condition marked by calcium buildup in the skin and subcutaneous tissues. Calcinosis cutis can range in intensity from little nodules in one area of the body to huge, crippling lesions affecting a vast portion of the body.[1] Five kinds of the condition are typically distinguished: calciphylaxis, idiopathic calcification, iatrogenic calcification, dystrophic calcification, and metastatic calcification.[2]
Calcinosis cutis | |
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Other names | Cutaneous calcification |
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Micrograph of calcinosis cutis. The calcification is purple (bottom of image). H&E stain. | |
Specialty | Dermatology ![]() |
Tumors, inflammation, varicose veins, infections, connective tissue disease, hyperphosphatemia, and hypercalcemia can all lead to calcinosis. Systemic sclerosis is linked to calcineuris cutis.[3] Calcinosis is seen in Limited Cutaneous Systemic Sclerosis, also known as CREST syndrome (the "C" in CREST).[4]